Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | GHSR | Q92847 | 1/20 | 0.58 |
| ▸ | HPGDS | O60760 | 1/20 | 0.58 |
| ▸ | CTSC | P53634 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | NPY4R | P50391 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291268 | 1.00 | ECE1 (0.69) | ECE1KDM4EMEN1LMNAMPO | |
| SCHEMBL30799684 | 0.93 | ECE1 (0.64) | ECE1 | |
| SCHEMBL13725698 | 0.93 | ECE1 (0.64) | ECE1 | |
| SCHEMBL31722484 | 0.93 | KDM4E (0.62) | ECE1KDM4EMEN1LMNAMPO | |
| SCHEMBL22133113 | 0.93 | ECE1 (0.64) | ECE1 | |
| SCHEMBL31748032 | 0.93 | ECE1 (0.66) | ECE1KDM4EMEN1LMNAMPO | |
| Hydrochloric Acid SCHEMBL8982603 | 0.92 | KDM4E (0.60) | ECE1KDM4EMEN1LMNAMPO | |
| SCHEMBL31606512 | 0.92 | ECE1 (0.65) | ECE1KDM4EMEN1LMNAMPO | |
| SCHEMBL31436156 | 0.92 | KDM4E (0.60) | ECE1KDM4EMEN1LMNAMPO | |
| SCHEMBL5583839 | 0.90 | ACE (0.72) | ECE1KDM4EMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | ECE1 1086/4885KDM4E 3630/4885MEN1 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.