Demannose

Demannose

SCHEMBL2317892

CC(C)=O.CC(C)=O.O=C[C@H](O)[C@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
PDE4A P27815 1/20 0.45
USP2 O75604 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
KDM4E B2RXH2 2/20 0.40
AKR1B1 P15121 1/20 0.37
TOP1 P11387 1/20 0.33
PAX8 Q06710 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
MPI P34949 1/20 0.31
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Galactose SCHEMBL7892167 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL9123753 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL9468628 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL9453431 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL344073 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL8340896 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL23929880 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Galactose SCHEMBL7895408 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL8213035 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
Demannose SCHEMBL28123189 1.00 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104031099-B A kind of sugar compounds containing two propylidene base takes off the catalysis process of propylidene CARBOTANG BIOTECH Co.,Ltd. (CN) 2016-03-02 CN disclosed
CN-104031099-A Method for catalyzing propylidene removal of dual-propylidene sugar compound CARBOTANG LTD 2014-09-10 CN disclosed
WO-2011095772-A2 NOVEL IMINOSUGAR THERAPEUTICS SUMMIT CORPORATION PLC (GB) 2011-08-11 WO disclosed
US-6117988-A Nucleotides and oligonucleotides preparable therefrom ADVANCED RESEARCH & TECHNOLOGY INSTITUTE (US) 2000-09-12 US disclosed
US-5536823-A 3'-sulfonyl nucleoside compounds INDIANA UNIVERSITY FOUNDATION (US) 1996-07-16 US disclosed
EP-0322395-B1 HETEROCYCLIC COMPOUNDS FOR INHIBITING VIRUS Monsanto Company (US) 1993-03-24 EP disclosed
US-5089520-A Administering 1,4-dideoxy-1,4-imino-L-arabinitol or 1,4-dideoxy-1,4-imino-D-ribitol; human immunodeficiency virus MONSANTO COMPANY (US) 1992-02-18 US disclosed
US-5043416-A Method of inhibiting virus MONSANTO COMPANY (US) 1991-08-27 US disclosed
US-4999360-A Treatment of AIDS, polyhydroxy piperidine derivatives MONSANTO COMPANY (US) 1991-03-12 US disclosed
EP-0371837-A2 Process for the synthesis of esters of dithiocarbamic acids by substitution of hydroxylated positions of mono- or polyhydroxylated molecules, products of this process and their uses PASTEUR MERIEUX SERUMS ET VACCINS (FR) 1990-06-06 EP disclosed
WO-1990005135-A2 PROCESS FOR THE SPECIFIC SYNTHESIS OF NEW DITHIOCARBAMIC ACID ESTERS BY SUBSTITUTING HYDROXYLATED SITES ON MONO- OR POLYHYDROXYLATED MOLECULES; PRODUCTS OBTAINED BY THIS PROCESS AND THEIR APPLICATION PASTEUR MERIEUX SERUMS ET VACCINS (FR) 1990-05-17 WO disclosed
EP-0322395-A1 Heterocyclic compounds for inhibiting virus Monsanto Company (US) 1989-06-28 EP disclosed