Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.31 |
| ▸ | CDK2 | P24941 | 9/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23180387 | 0.85 | HCRTR2 (0.40) | HCRTR2CDC7DBF4JAK2JAK3 | |
| SCHEMBL23146178 | 0.84 | CDC7 (0.56) | HCRTR2CDC7DBF4JAK2JAK3 | |
| SCHEMBL23159723 | 0.76 | HCRTR2 (0.55) | HCRTR2CDC7DBF4HSD17B10KDM4E | |
| SCHEMBL15889436 | 0.74 | HCRTR2 (0.51) | HCRTR2CDC7DBF4HSD17B10KDM4E | |
| SCHEMBL23180250 | 0.73 | CDC7 (0.43) | CDC7DBF4HSD17B10MEN1ALDH1A1 | |
| SCHEMBL15896608 | 0.73 | HCRTR2 (0.50) | HCRTR2CDC7DBF4HSD17B10KDM4E | |
| SCHEMBL15376175 | 0.68 | HCRTR2 (0.48) | HCRTR2CDC7DBF4HSD17B10KDM4E | |
| SCHEMBL31705326 | 0.68 | HCRTR2 (0.48) | HCRTR2CDC7DBF4HSD17B10KDM4E | |
| SCHEMBL30908652 | 0.68 | HCRTR2 (0.48) | HCRTR2CDC7DBF4HSD17B10HPGD | |
| SCHEMBL31706651 | 0.68 | CDC7 (0.53) | HCRTR2CDC7DBF4HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021062318-A1 | THIAZOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | THE GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT, INC. (US) | 2021-04-01 | — | — | WO | disclosed |