Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | IGF2BP1 | Q9NZI8 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | STAT3 | P40763 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amarin SCHEMBL22433345 | 1.00 | ITGAL (1.00) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 | |
| Cucurbitacin B SCHEMBL29602393 | 1.00 | ITGAL (1.00) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 | |
| Amarin SCHEMBL10013358 | 1.00 | ITGAL (1.00) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 | |
| Amarin SCHEMBL20121442 | 1.00 | ITGAL (1.00) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 | |
| Amarin SCHEMBL18177462 | 1.00 | ITGAL (1.00) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 | |
| Amarin SCHEMBL13668120 | 1.00 | ITGAL (1.00) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 | |
| Amarin SCHEMBL17531553 | 1.00 | ITGAL (1.00) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 | |
| Amarin SCHEMBL19186443 | 1.00 | ITGAL (1.00) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 | |
| Amarin SCHEMBL30863648 | 0.99 | ITGAL (0.98) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 | |
| Cucurbitacin E SCHEMBL29908892 | 0.92 | ITGAL (0.84) | ITGALNPC1RAB9AIGF2BP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1048 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122031598-A | Preparation method and application of nephritis medicine | 五源本草(山东)健康科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122012585-A | Application of CmBt and CmBr genes in regulating and controlling bitter taste of melon fruits | 青岛农业大学 | 2026-05-12 | — | — | CN | claimed |
| US-20250325717-A1 | ANTI-NUCLEOPHOSMIN 1 ANTIBODY AND ANTIBODY CONJUGATE COMBINATION THERAPIES | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-10-23 | — | — | US | claimed |
| US-20250313647-A1 | MUTANT AND MISLOCALIZED CELL SURFACE NUCLEOPHOSMIN 1 AS A DIAGNOSTIC AND THERAPEUTIC TARGET OF HUMAN DISEASE | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-10-09 | — | — | US | claimed |
| EP-4603108-A1 | HUMAN SERUM ALBUMIN BASED NANOCARRIERS FOR TARGETED IMMUNOTHERAPY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-08-20 | — | — | EP | claimed |
| CN-119925642-A | Nanostructure liposome and preparation method thereof | 齐鲁理工学院 | 2025-05-06 | — | — | CN | claimed |
| US-12285488-B2 | Oral dosage form containing theobromine-free cocoa | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2025-04-29 | — | — | US | claimed |
| WO-2025073376-A1 | MASKING PREPARATIONS AND COMPOUNDS FROM DAEMONOROPS DRACO (DRAGON BLOOD) | SYMRISE AG (DE) | 2025-04-10 | — | — | WO | claimed |
| CN-119707846-A | Method for preparing cucurbitacin B derivative by strong acid dehydration and peroxy acid oxidation and application | 常州大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119677779-A | Combination therapy with anti-nucleolin 1 antibodies and antibody conjugates | 儿童医学中心公司 | 2025-03-21 | — | — | CN | claimed |
| CN-1883484-A | Novel pharmacological use of cucurbitacine | UNIV SHENYANG PHARMACEUTICAL (CN) | 2006-12-27 | — | — | CN | claimed |
| US-20060246161-A1 | METHOD OF MAKING MEDICAMENT FOR TREATING ANEMIA | ULTRA BIOTECH LIMITED (GB) | 2006-11-02 | — | — | US | claimed |
| CN-1698620-A | Cucurbitacin emulsion capable of filtering out and eliminating bacteria and preparation method thereof | UNIV SHENYANG PHARMACEUTICAL (CN) | 2005-11-23 | — | — | CN | claimed |
| CN-1600316-A | Drop Pills of cucurbitacin medication and preparation method | BOERDA BIOTECH DEV CO LTD BEIJ (CN) | 2005-03-30 | — | — | CN | claimed |
| CN-1513450-A | Injection of compound pancreatic alcohol | 周宝义 | 2004-07-21 | — | — | CN | claimed |
| US-20040138189-A1 | Moderation of intracellular signals; antitumor agents; drug screening; administering cucurbitacin compound | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-07-15 | — | — | US | claimed |
| CN-1504191-A | Cucurbitacin lipsome preparation method and formulation | 沈阳药科大学 | 2004-06-16 | — | — | CN | claimed |
| CN-1405187-A | Cucurbitacine cyclodextrin clathrate and preparation thereof | SHENGYANG MEDICINE UNIV (CN) | 2003-03-26 | — | — | CN | claimed |
| WO-2002078617-A2 | MATERIALS AND METHODS FOR TREATMENT OF CANCER AND IDENTIFICATION OF ANTI-CANCER COMPOUNDS | UNIVERSITY OF SOUTH FLORIDA (US) | 2002-10-10 | — | — | WO | claimed |
| US-5925356-A | Method of isolating cucurbitacin | JP MORGAN CHASE BANK | 1999-07-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246161-A1 | METHOD OF MAKING MEDICAMENT FOR TREATING ANEMIA | HBG1, HBG2, HBZ | ITGAL 1266/4885NPC1 4579/4885RAB9A 4595/4885 |
| US-20040138189-A1 | Moderation of intracellular signals; antitumor agents; drug screening; administering cucurbitacin compound | STAT3, STAT1, JAK2 | ITGAL 4681/4885NPC1 1707/4885RAB9A 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.