Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.30 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12240425 | 0.81 | KDM4E (0.40) | KDM4EPDGFRBPDGFRAPSMB5HRH4 | |
| SCHEMBL12240466 | 0.79 | KDM4E (0.39) | KDM4EPDGFRBPDGFRAPSMB5HRH4 | |
| SCHEMBL21446933 | 0.78 | ADRB3 (0.39) | KDM4EPDGFRBPDGFRAPSMB5PIP4K2A | |
| SCHEMBL21367908 | 0.78 | KDM4E (0.38) | KDM4EPDGFRBPDGFRAPSMB5HRH4 | |
| SCHEMBL31703760 | 0.78 | KDM4E (0.38) | KDM4EPDGFRBPDGFRAPSMB5HRH4 | |
| SCHEMBL16139570 | 0.78 | CHRNB2 (0.41) | KDM4EPDGFRBPDGFRAPSMB5HRH4 | |
| SCHEMBL21712544 | 0.78 | KDM4E (0.38) | KDM4EPDGFRBPDGFRAPSMB5HRH4 | |
| SCHEMBL595151 | 0.78 | KDM4E (0.38) | KDM4EPDGFRBPDGFRAPSMB5 | |
| SCHEMBL29911758 | 0.75 | KDM4E (0.39) | KDM4EPDGFRBPDGFRAPSMB5HRH4 | |
| SCHEMBL23872356 | 0.75 | KDM4E (0.36) | KDM4EPDGFRBPDGFRAPSMB5HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057975-A1 | MUTANT IDH2 INHIBITOR AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2021-04-01 | — | — | WO | disclosed |