Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869948 | 0.81 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL18290086 | 0.80 | TLR2 (0.33) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL18290137 | 0.78 | LTB4R (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| Nitric Acid SCHEMBL3869559 | 0.73 | LTB4R (0.32) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL14574000 | 0.72 | CYP3A4 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL5155697 | 0.72 | CYP3A4 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL4264816 | 0.72 | CYP3A4 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL31645470 | 0.71 | SMYD2 (0.34) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL28946557 | 0.71 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL28946558 | 0.71 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3302570-B1 | TRIMALEIMIDE LINKERS AND USES THEREOF | NEWBIO THERAPEUTICS INC (CN) | 2021-03-31 | — | — | EP | disclosed |