Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19161952 | 0.89 | TNKS (0.45) | TNKSTNKS2MAPTPIM1PIM2 | |
| SCHEMBL19161619 | 0.87 | TNKS (0.47) | TNKSTNKS2MAPTPIM1PIM2 | |
| SCHEMBL19162670 | 0.87 | TNKS (0.46) | TNKSTNKS2MAPTPIM1PIM2 | |
| SCHEMBL23473704 | 0.86 | TNKS (0.42) | TNKSTNKS2MAPTPIM1PIM2 | |
| SCHEMBL24623026 | 0.83 | TNKS (0.38) | TNKSTNKS2MAPTPIM1PIM2 | |
| SCHEMBL23184019 | 0.81 | TNKS (0.39) | TNKSTNKS2MAPTPIM1PIM2 | |
| SCHEMBL23473642 | 0.81 | TNKS (0.39) | TNKSTNKS2MAPTPIM1PIM2 | |
| SCHEMBL20659764 | 0.80 | TNKS (0.40) | TNKSTNKS2MAPTPIM1PIM2 | |
| SCHEMBL16581199 | 0.79 | TNKS (0.39) | TNKSTNKS2MAPTPIM1PIM2 | |
| SCHEMBL23473641 | 0.78 | TNKS (0.36) | TNKSTNKS2MAPTPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968230-B2 | Spiro-structured compound and organic electronic device comprising same | LG CHEM, LTD. | 2021-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968230-B2 | Spiro-structured compound and organic electronic device comprising same | ESR1, OR10J3, ERG | TNKS 4030/4885TNKS2 4072/4885MAPT 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.