SCHEMBL23473642

SCHEMBL23473642

CC(C)(C)c1nc(-c2ccc3c(c2)-c2ccccc2C3(C)C)c2sc3ccccc3c2n1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TNKS O95271 2/20 0.39
▸ TNKS2 Q9H2K2 2/20 0.39
▸ ALOX5 P09917 1/20 0.31
▸ MAPT P10636 1/20 0.30
▸ PIM1 P11309 1/20 0.30
▸ PIM2 Q9P1W9 1/20 0.30
▸ LIMK1 P53667 1/20 0.30
▸ CNR1 P21554 1/20 0.30
▸ CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23184019 0.94 TNKS (0.39) TNKSTNKS2ALOX5MAPTPIM1
SCHEMBL23874643 0.90 TNKS (0.35) TNKSTNKS2MAPTPIM1PIM2
SCHEMBL23920358 0.83 TNKS (0.34) TNKSTNKS2ALOX5MAPTPIM1
SCHEMBL23874644 0.83 — —
SCHEMBL23184018 0.81 TNKS (0.46) TNKSTNKS2ALOX5MAPTPIM1
SCHEMBL19106204 0.80 MEN1 (0.37) TNKSTNKS2ALOX5MAPTPIM1
SCHEMBL24127783 0.80 TNKS (0.32) TNKSTNKS2ALOX5PIM1PIM2
SCHEMBL24127779 0.80 TNKS (0.32) TNKSTNKS2ALOX5PIM1PIM2
SCHEMBL19161952 0.80 TNKS (0.45) TNKSTNKS2MAPTPIM1PIM2
SCHEMBL18859537 0.80 TNKS (0.36) TNKSTNKS2ALOX5MAPTPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11725138-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-08-15 — — US disclosed
US-11725138-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-08-15 — — US disclosed
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-11-10 — — US disclosed
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-06-02 — — US disclosed
US-20220045281-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-10 — — US disclosed
US-20210320263-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-14 — — US disclosed
US-20210175433-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-06-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, SOD1, NECTIN4 TNKS 809/4885TNKS2 733/4885ALOX5 832/4885
US-20220045281-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, ICOSLG, OR10J3 TNKS 3335/4885TNKS2 3029/4885ALOX5 559/4885
US-11725138-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same OR10J3, ICOSLG, TRPM4 TNKS 2162/4885TNKS2 2442/4885ALOX5 588/4885
US-20210175433-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, ICOSLG, TRPM4 TNKS 2162/4885TNKS2 2442/4885ALOX5 588/4885
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, OR10J3 TNKS 2226/4885TNKS2 3228/4885ALOX5 467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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