Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 13/20 | 0.75 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.75 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.75 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.75 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.75 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071844 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL1931918 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL19697632 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL8659794 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL24408031 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL8435259 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL24999988 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL18827757 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL24001462 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL16361266 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240068007-A1 | BIOMARKERS OF RISK FOR INFECTION | THE UNIVERSITY OF CHICAGO | 2024-02-29 | — | — | US | claimed |
| US-20240058454-A1 | BIOLOGICAL DELIVERY SYSTEMS | PARTICELLA INC (US) | 2024-02-22 | — | — | US | claimed |
| CN-117241780-A | Biological delivery system | 帕帝塞拉公司 | 2023-12-15 | — | — | CN | claimed |
| CN-116445434-A | 12 alpha-HSDH enzyme mutant with improved catalytic activity and application thereof | 中山百灵生物技术股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| US-11634743-B2 | Coupled, self-sufficient biotransformation of chenodeoxcholic acid to ursodeoxycholic acid and novel enzyme mutants applicable in said process | PHARMAZELL GMBH (DE) | 2023-04-25 | — | — | US | claimed |
| CN-113960222-B | Serum sample-based bile acid full-channel metabolic profile detection method and application thereof | 中国中医科学院医学实验中心 | 2022-02-25 | — | — | CN | claimed |
| CN-113960221-B | Method for detecting bile acid full-channel metabolic profile based on fecal sample and application thereof | 中国中医科学院医学实验中心 | 2022-02-25 | — | — | CN | claimed |
| CN-113960222-A | Serum sample-based bile acid full-channel metabolic profile detection method and application thereof | 中国中医科学院医学实验中心 | 2022-01-21 | — | — | CN | claimed |
| CN-113960221-A | Method for detecting bile acid full-channel metabolic profile based on fecal sample and application thereof | 中国中医科学院医学实验中心 | 2022-01-21 | — | — | CN | claimed |
| US-20200407766-A1 | Coupled, Self-Sufficient Biotransformation of Chenodeoxcholic Acid to Ursodeoxycholic Acid and Novel Enzyme Mutants Applicable in said Process | PHARMAZELL GMBH (DE) | 2020-12-31 | — | — | US | claimed |
| EP-2576600-B1 | NOVEL 7ALPHA-HYDROXYSTEROID DEHYDROGENASE KNOCKOUT MUTANTS AND USE THEREOF | PHARMAZELL GMBH (DE) | 2018-01-24 | — | — | EP | claimed |
| WO-2017220486-A2 | COUPLED, SELF-SUFFICIENT BIOTRANSFORMATION OF CHENODEOXYCHOLIC ACID TO URSODEOXYCHOLIC ACID AND NOVEL ENZYME MUTANTS APPLICABLE IN SAID PROCESS | PHARMAZELL GMBH (DE) | 2017-12-28 | — | — | WO | claimed |
| US-9096825-B2 | 7 α-hydroxysteroid dehydrogenase knockout mutants and use therefor | PHARMAZELL GMBH (DE) | 2015-08-04 | — | — | US | claimed |
| US-20140147887-A1 | NOVEL 12 ALPHA-HYDROXYSTEROID DEHYDROGENASES, PRODUCTION AND USE THEREOF | PHARMAZELL GMBH (DE) | 2014-05-29 | — | — | US | claimed |
| US-20130224792-A1 | Novel 7 alpha-Hydroxysteroid Dehydrogenase Knockout Mutants and Use Therefor | PHARMAZELL GMBH (DE) | 2013-08-29 | — | — | US | claimed |
| US-7851174-B2 | Method for quantitatively determining cholesterol in high density lipoproteins and reagents therefor | KYOWA MEDEX CO., LTD. (JP) | 2010-12-14 | — | — | US | claimed |
| US-20090226944-A1 | METHOD FOR MEASURING TRIGLYCERIDE IN LOW-DENSITY LIPOPROTEIN AND KIT FOR MEASUREMENT | KYOWA MEDEX CO., LTD. (JP) | 2009-09-10 | — | — | US | claimed |
| EP-1953240-A1 | METHOD FOR MEASURING TRIGLYCERIDE IN LOW-DENSITY LIPOPROTEIN AND KIT FOR MEASUREMENT | Kyowa Medex Co., Ltd. (JP) | 2008-08-06 | — | — | EP | claimed |
| US-20050287619-A1 | Method and reagent for measuring cholesterol in high-density lipoproteins | KYOWA MEDEX CO., LTD. (JP) | 2005-12-29 | — | — | US | claimed |
| EP-1555327-A1 | METHOD AND REAGENT FOR MEASURING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEINS | Kyowa Medex Co., Ltd. (JP) | 2005-07-20 | — | — | EP | claimed |