Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.56 |
| ▸ | MMEL1 | Q495T6 | 5/20 | 0.52 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318629 | 1.00 | MME (0.56) | MMEMMEL1FFAR2PSMB5PSMB8 | |
| SCHEMBL2312644 | 0.93 | MME (0.54) | MMEMMEL1FFAR2PSMB5PSMB8 | |
| SCHEMBL2312636 | 0.93 | MME (0.54) | MMEMMEL1FFAR2PSMB5PSMB8 | |
| SCHEMBL2313611 | 0.86 | MME (0.58) | MMEMMEL1FFAR2PSMB5PSMB8 | |
| SCHEMBL2313603 | 0.86 | MME (0.58) | MMEMMEL1FFAR2PSMB5PSMB8 | |
| SCHEMBL2315209 | 0.86 | MME (0.50) | MMEMMEL1FFAR2PSMB5PSMB8 | |
| SCHEMBL2315216 | 0.86 | MME (0.50) | MMEMMEL1FFAR2PSMB5PSMB8 | |
| SCHEMBL2312999 | 0.86 | FFAR2 (0.60) | MMEFFAR2PSMB5PSMB8 | |
| SCHEMBL2312991 | 0.86 | FFAR2 (0.60) | MMEFFAR2PSMB5PSMB8 | |
| SCHEMBL2317683 | 0.86 | MME (0.63) | MMEMMEL1FFAR2PSMB5PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |