⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289429 | 0.83 | PIK3CD (0.31) | — | |
| SCHEMBL18946495 | 0.83 | PIK3CD (0.31) | — | |
| SCHEMBL20793850 | 0.83 | PIK3CD (0.31) | — | |
| SCHEMBL13896140 | 0.80 | PDE8B (0.33) | — | |
| SCHEMBL8861108 | 0.80 | — | — | |
| SCHEMBL27554205 | 0.80 | PDE8B (0.33) | — | |
| SCHEMBL18860234 | 0.78 | — | — | |
| SCHEMBL3965479 | 0.77 | PDE8B (0.32) | — | |
| SCHEMBL15107625 | 0.77 | — | — | |
| SCHEMBL15107682 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242335-B2 | Fluorine-substituted indazole compounds and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-02-08 | — | — | US | disclosed |
| US-20210101882-A1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-04-08 | — | — | US | disclosed |