Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554205 | 1.00 | PDE8B (0.33) | PDE8B | |
| SCHEMBL20793850 | 0.83 | PIK3CD (0.31) | — | |
| SCHEMBL18946495 | 0.83 | PIK3CD (0.31) | — | |
| SCHEMBL7289429 | 0.83 | PIK3CD (0.31) | — | |
| SCHEMBL18542421 | 0.81 | — | — | |
| SCHEMBL3965479 | 0.81 | PDE8B (0.32) | PDE8B | |
| SCHEMBL15107625 | 0.81 | — | — | |
| SCHEMBL23186758 | 0.80 | — | — | |
| SCHEMBL8861108 | 0.80 | — | — | |
| SCHEMBL8206969 | 0.78 | PDE8B (0.30) | PDE8B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074108-B1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2012-11-21 | — | — | EP | disclosed |