Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962965 | 0.88 | ENPP2 (0.66) | ENPP2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL4875063 | 0.85 | ENPP2 (0.67) | ENPP2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL18032530 | 0.79 | ENPP2 (0.58) | ENPP2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL13521537 | 0.79 | MEN1 (0.57) | ENPP2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL10304113 | 0.77 | MEN1 (0.58) | MEN1KMT2AEPHX2EPHX1ALDH1A1 | |
| SCHEMBL28333058 | 0.77 | MEN1 (0.58) | MEN1KMT2AEPHX2EPHX1ALDH1A1 | |
| SCHEMBL6975151 | 0.77 | KMT2A (0.67) | ENPP2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL31481320 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL20771790 | 0.77 | CHRM4 (0.52) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 | |
| SCHEMBL14428335 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ACHRM4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021064077-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-08 | — | — | WO | disclosed |
| EP-3800188-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS | Bayer AG (DE) | 2021-04-07 | — | — | EP | disclosed |
| EP-3800188-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS | Bayer AG (DE) | 2021-04-07 | — | — | EP | disclosed |