SCHEMBL23188

SCHEMBL23188

COc1cccc(C=O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.65
RAB9A P51151 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
CHRM5 P08912 1/20 0.62
RELA Q04206 1/20 0.60
NFE2L2 Q16236 2/20 0.56
SRC P12931 1/20 0.56
FBP1 P09467 1/20 0.56
ALDH1A1 P00352 2/20 0.56
CYP2A6 P11509 1/20 0.56
CYP19A1 P11511 1/20 0.55
NQO2 P16083 1/20 0.55
CHRM2 P08172 1/20 0.54
CHRM1 P11229 1/20 0.54
CHRM3 P20309 1/20 0.54
POLB P06746 1/20 0.54
TUBB4A P04350 1/20 0.53
TUBB P07437 1/20 0.53
TUBA3C P0DPH7 1/20 0.53
TUBA1B P68363 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29399968 1.00 NPC1 (0.65) NPC1RAB9ATDP1CHRM5RELA
SCHEMBL7684603 1.00 NPC1 (0.65) NPC1RAB9ATDP1CHRM5RELA
SCHEMBL29998099 0.98 NPC1 (0.63) NPC1RAB9ATDP1CHRM5RELA
Ethane SCHEMBL1494210 0.98 NPC1 (0.63) NPC1RAB9ATDP1CHRM5RELA
Naphthalene SCHEMBL28157566 0.92 NPC1 (0.58) NPC1RAB9ATDP1CHRM5RELA
SCHEMBL17099392 0.92 NPC1 (0.58) NPC1RAB9ATDP1CHRM5RELA
Alcohol SCHEMBL28509882 0.91 NPC1 (0.60) NPC1RAB9ATDP1CHRM5RELA
3-Hydroxybenzaldehyde SCHEMBL10799855 0.91 ABL1 (0.62) NPC1RAB9ATDP1CHRM5RELA
Ethylene Glycol SCHEMBL28606580 0.91 NPC1 (0.60) NPC1RAB9ATDP1CHRM5RELA
Sulfuric Acid SCHEMBL8608191 0.91 NPC1 (0.56) NPC1RAB9ATDP1CHRM5RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6865 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071445-A Aldol condensation method 中国科学院大连化学物理研究所 2026-05-22 CN claimed
CN-121574130-A Synthesis method of pyrazolo [1,2-b ] phthalazine-5, 10-dione derivative as drug intermediate and catalytic system for synthesis 南京苏亦欣医药科技有限公司 2026-02-27 CN claimed
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4205741-B1 CYP2E1 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY-MEDIATED DISEASES SUZHOU LINGXI BIOTECHNOLOGY CO LTD (CN) 2025-12-10 EP claimed
CN-120136800-A Single-excitation visible and near-infrared double-region emission small molecule fluorescent probe and preparation method and application thereof 南京工业大学 2025-06-13 CN claimed
CN-120040358-A Preparation method and application of quinazoline derivative containing chalcone 沈阳工业大学 2025-05-27 CN claimed
CN-116606265-B Protocatechu derivative and synthesis method and application thereof 山西大学 2025-05-02 CN claimed
CN-119899184-A Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease 中国人民解放军北部战区总医院 2025-04-29 CN claimed
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN claimed
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
WO-1994029288-A1 Δ6,7-TAXOLS ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM THE UPJOHN COMPANY (US) 1994-12-22 WO claimed
CN-1095377-A 7-halo-and 7 beta, 8 beta-methylene-paclitaxel, antitumor use and pharmaceutical composition containing the same UPJOHN CO (US) 1994-11-23 CN claimed
WO-1994013655-A1 7-HALO- AND 7β,8β-METHANO-TAXOLS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM THE UPJOHN COMPANY (US) 1994-06-23 WO claimed
EP-0430485-A2 Quinoline compound UBE INDUSTRIES, LTD. (JP) 1991-06-05 EP claimed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 US claimed
US-4435572-A FROM 3-METHOXYBENZALDEHYDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1984-03-06 US claimed
US-4358596-A Process for the preparation of 1,2,3-thiadiazol-5-yl ureas SCHERING AG (DE) 1982-11-09 US claimed
US-3975532-A ANALGESIC ICI UNITED STATES INC. (US) 1976-08-17 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed
US-3946067-A Process for the preparation of aromatic aldehydes NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1976-03-23 US claimed