Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.58 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19068940 | 0.93 | HPGDS (0.58) | HPGDSCD274HPGDTP53POLB | |
| SCHEMBL14916353 | 0.88 | HPGDS (0.56) | HPGDSCD274HPGDTP53POLB | |
| SCHEMBL16724770 | 0.86 | HPGDS (0.54) | HPGDSCD274HPGDTP53POLB | |
| SCHEMBL14916579 | 0.83 | HPGDS (0.54) | HPGDSCD274HPGDPOLBALDH1A1 | |
| SCHEMBL30406116 | 0.83 | HPGDS (0.54) | HPGDSCD274HPGDPOLBALDH1A1 | |
| SCHEMBL2551435 | 0.78 | TNKS2 (0.50) | HPGDSCD274HPGDPOLBALDH1A1 | |
| SCHEMBL14930164 | 0.78 | ERN1 (0.49) | HPGDSCD274HPGDPOLBALDH1A1 | |
| SCHEMBL14924895 | 0.78 | ERN1 (0.63) | HPGDSCD274HPGDPOLBMEN1 | |
| SCHEMBL14930118 | 0.77 | HPGDS (0.55) | HPGDSCD274HPGDPOLBALDH1A1 | |
| SCHEMBL14930117 | 0.76 | CD274 (0.53) | HPGDSCD274HPGDPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3799870-A1 | IRE-1A INHIBITORS | Fosun Orinove Pharmatech, Inc. (CN) | 2021-04-07 | — | — | EP | disclosed |
| US-9517977-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-12-13 | — | — | US | disclosed |