Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319218 | 0.83 | FNTA (0.42) | RAB9ANPC1GAASMN1; SMN2HDAC1 | |
| SCHEMBL2320555 | 0.80 | HDAC1 (0.40) | RAB9ANPC1GAASMN1; SMN2HDAC1 | |
| SCHEMBL2315751 | 0.78 | HDAC1 (0.45) | RAB9ANPC1GAASMN1; SMN2HDAC1 | |
| SCHEMBL2317080 | 0.76 | RAB9A (0.56) | RAB9ANPC1GAASMN1; SMN2KMT2A | |
| SCHEMBL2320718 | 0.76 | DEGS1 (0.43) | RAB9ANPC1GAASMN1; SMN2HDAC1 | |
| SCHEMBL2320166 | 0.74 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL2319592 | 0.74 | KCNQ3 (0.42) | HDAC1HDAC2HDAC8HDAC6DEGS1 | |
| SCHEMBL2317845 | 0.74 | KMT2A (0.67) | RAB9ANPC1HDAC1HDAC2KMT2A | |
| SCHEMBL6361072 | 0.72 | NPSR1 (0.40) | RAB9ANPC1GAASMN1; SMN2KMT2A | |
| SCHEMBL2318039 | 0.72 | MAPK8 (0.47) | RAB9ANPC1SMN1; SMN2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102272120-B | Biologically active amides | LUNDBECK & CO AS H | 2013-12-25 | — | — | CN | disclosed |
| CN-102272120-A | Biologically active amides | — | 2011-12-07 | — | — | CN | disclosed |
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| EP-2352730-A2 | BIOLOGICALLY ACTIVE AMIDES | H. Lundbeck A/S (DK) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | NPY5R, NPY1R, NPY2R | RAB9A 3184/4885NPC1 1717/4885GAA 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.