SCHEMBL23188773

SCHEMBL23188773

C1=Cc2c(c3ccccc3n2-c2ccc(-c3cccc(-n4c5ccccc5c5ccccc54)c3)cc2)CC1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.40
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HDAC4 P56524 1/20 0.33
FAAH O00519 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
MGLL Q99685 1/20 0.31
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12691245 0.95 KDM4E (0.38) ATMKDM4EL3MBTL1HDAC4
SCHEMBL12292096 0.95 ATM (0.40) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL23352293 0.94 KDM4E (0.35) ATMKDM4EL3MBTL1HDAC4
SCHEMBL17012686 0.93 ATM (0.39) ATMKDM4EL3MBTL1HDAC4FAAH
SCHEMBL22186195 0.93 ATM (0.36) ATMKDM4EL3MBTL1HDAC4FAAH
SCHEMBL12234498 0.93 KDM4E (0.40) ATMKDM4EL3MBTL1HDAC4KMT2A
SCHEMBL10125208 0.93 KDM4E (0.40) ATMKDM4EL3MBTL1HDAC4KMT2A
SCHEMBL12964101 0.93 ATM (0.38) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL23570679 0.93 ALDH1A1 (0.37) ATMKDM4EL3MBTL1FAAHALDH1A1
SCHEMBL22076998 0.93 KDM4E (0.33) ATMKDM4EL3MBTL1HDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11575092-B2 Organic light-emitting device and apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-07 US disclosed
US-20210104689-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-08 US disclosed