Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558898 | 1.00 | APAF1 (0.51) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL1452939 | 1.00 | APAF1 (0.51) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL8520662 | 0.86 | APAF1 (0.59) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL11780395 | 0.86 | APAF1 (0.45) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL24709576 | 0.85 | ANPEP (0.44) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL1454104 | 0.84 | PPARG (0.46) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL2387476 | 0.82 | KMT2A (0.58) | KDM4EPPARGPPARAHPGDALDH1A1 | |
| SCHEMBL16995424 | 0.82 | TSHR (0.50) | APAF1KDM4EPOLBMAPTRECQL | |
| SCHEMBL14483930 | 0.82 | ANPEP (0.43) | PPARGPPARATSHRHPGDANPEP | |
| SCHEMBL7386121 | 0.81 | CYP1A2 (0.55) | PPARGPPARATSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464324-B1 | ANGIOTENSIN-1-RECEPTOR ANTAGONISTS | FERRING BV (NL) | 2021-04-07 | — | — | EP | disclosed |