SCHEMBL231899

SCHEMBL231899

COc1cccc([C@H](C)NC(=O)CNC(=O)Nc2ccc(C(=N)N)cc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F7 P08709 20/20 1.00
F2 P00734 13/20 1.00
F10 P00742 3/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2802124 1.00 F7 (1.00) F7F2F10
SCHEMBL4231819 0.91 F7 (0.84) F7F2F10
SCHEMBL4231809 0.91 F7 (0.84) F7F2F10
SCHEMBL4231817 0.91 F7 (0.84) F7F2F10
SCHEMBL3863203 0.91 F7 (0.84) F7F2F10
SCHEMBL4958022 0.86 F7 (0.75) F7F2F10
SCHEMBL4958055 0.86 F7 (0.75) F7F2F10
SCHEMBL13993084 0.86 F7 (0.75) F7F2F10
SCHEMBL13936352 0.85 F7 (1.00) F7F2F10
SCHEMBL235788 0.85 F7 (1.00) F7F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1656158-B1 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTHCARE AG (CH) 2016-03-09 EP claimed
US-20130084274-A1 Liquid, Aqueous Pharmaceutical Compositions of Factor VII Polypeptides NOVO NORDISK HEALTH CARE AG (CH) 2013-04-04 US claimed
US-8318904-B2 Liquid, aqueous pharmaceutical compositions of factor VII polypeptides NOVO NORDISK HEALTH CARE AG (CH) 2012-11-27 US claimed
US-20120003206-A1 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITIONS OF FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTHCARE A/G (CH) 2012-01-05 US claimed
US-7732405-B2 Liquid, aqueous pharmaceutical compositions of factor VII polypeptides NOVO NORDISK HEALTH CARE AG (CH) 2010-06-08 US claimed
US-20060205648-A1 Liquid, aqueous pharmaceutical compositions of factor VII polypeptides NOVO NORDISK HEALTHCARE A/G (CH) 2006-09-14 US claimed
EP-1656158-B1 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTHCARE AG (CH) 2016-03-09 EP disclosed
EP-1656158-B1 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTHCARE AG (CH) 2016-03-09 EP disclosed
US-20150273027-A1 LIQUID PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDE NOVO NORDISK HEALTHCARE AG (CH) 2015-10-01 US disclosed
US-20130084274-A1 Liquid, Aqueous Pharmaceutical Compositions of Factor VII Polypeptides NOVO NORDISK HEALTH CARE AG (CH) 2013-04-04 US disclosed
US-8318904-B2 Liquid, aqueous pharmaceutical compositions of factor VII polypeptides NOVO NORDISK HEALTH CARE AG (CH) 2012-11-27 US disclosed
US-20120003206-A1 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITIONS OF FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTHCARE A/G (CH) 2012-01-05 US disclosed
US-8026214-B2 Liquid, aqueous pharmaceutical compositions of factor VII polypeptides NOVO NORDISK HEALTH CARE AG (CH) 2011-09-27 US disclosed
US-20100056453-A1 Liquid, Aqueous Pharmaceutical Compositions of Factor VII Polypeptides NOVO NORDISK HEALTHCARE A/G (CH) 2010-03-04 US disclosed
US-20100056453-A1 Liquid, Aqueous Pharmaceutical Compositions of Factor VII Polypeptides NOVO NORDISK HEALTHCARE A/G (CH) 2010-03-04 US disclosed
US-20090111751-A1 Method of Removing a Non-Metallic Protein Inhibitor From a Liquid Pharmaceutical Preparation NOVO NORDISK HEALTH CARE AG (CH) 2009-04-30 US disclosed
WO-2006128497-A1 PHARMACEUTICAL FORMULATION OF FACTOR XI NOVO NORDISK A/S (DK) 2006-12-07 WO disclosed
US-20060205648-A1 Liquid, aqueous pharmaceutical compositions of factor VII polypeptides NOVO NORDISK HEALTHCARE A/G (CH) 2006-09-14 US disclosed
EP-1656158-A2 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDES Novo Nordisk Health Care AG (CH) 2006-05-17 EP disclosed
WO-2005016365-A2 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTH CARE AG (CH) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150273027-A1 LIQUID PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDE F7, F8, F9 F7 1/4885F2 7/4885F10 11/4885
US-20060205648-A1 Liquid, aqueous pharmaceutical compositions of factor VII polypeptides F7, F5, F12 F7 1/4885F2 44/4885F10 16/4885
US-20120003206-A1 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITIONS OF FACTOR VII POLYPEPTIDES F7, F5, F12 F7 1/4885F2 40/4885F10 15/4885
US-20100056453-A1 Liquid, Aqueous Pharmaceutical Compositions of Factor VII Polypeptides F7, F5, F12 F7 1/4885F2 40/4885F10 15/4885
US-20130084274-A1 Liquid, Aqueous Pharmaceutical Compositions of Factor VII Polypeptides F7, F5, F12 F7 1/4885F2 40/4885F10 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.