SCHEMBL4231817

SCHEMBL4231817

COc1cccc(C(C)NC(=O)CNC(=O)Nc2cccc(C(=N)N)c2)c1

nearest known ligand 0.84

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F7 P08709 18/20 0.84
F2 P00734 12/20 0.84
F10 P00742 3/20 0.62
GPR139 Q6DWJ6 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4231809 1.00 F7 (0.84) F7F2F10GPR139
SCHEMBL4231819 1.00 F7 (0.84) F7F2F10GPR139
SCHEMBL2802124 0.91 F7 (1.00) F7F2F10
SCHEMBL231899 0.91 F7 (1.00) F7F2F10
SCHEMBL4225512 0.88 F7 (0.78) F7F2F10
SCHEMBL4225518 0.88 F7 (0.78) F7F2F10
SCHEMBL4231808 0.88 F7 (0.78) F7F2F10
SCHEMBL13993084 0.85 F7 (0.75) F7F2F10GPR139
SCHEMBL13855067 0.85 F7 (0.61) F7F2GPR139
SCHEMBL13855066 0.85 F7 (0.61) F7F2GPR139

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130085-A1 Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations NOVO NORDISH HEALTHCARE AG (CH) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090130085-A1 Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations F7, F5, F8 F7 1/4885F2 9/4885F10 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.