SCHEMBL23192536

SCHEMBL23192536

CC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 14/20 0.44
NPY1R P25929 9/20 0.44
NPY5R Q15761 8/20 0.44
NPY2R P49146 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18072614 0.93 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL21062302 0.93 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL19862400 0.93 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL21062366 0.93 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL18072613 0.88 NPY4R (0.42) NPY4RNPY1RNPY5RNPY2R
SCHEMBL21062362 0.87 CTSS (0.40) NPY4R
SCHEMBL19862037 0.87 CTSS (0.40) NPY4R
SCHEMBL19862385 0.87 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL21096611 0.87 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL18048887 0.86 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3800192-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-04-07 EP disclosed