Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810886 | 0.86 | OPRL1 (0.48) | USP2SMN1; SMN2POLBESR2OPRL1 | |
| SCHEMBL26066372 | 0.86 | USP2 (0.39) | USP2SMN1; SMN2AVPR1AGPR119ESR2 | |
| SCHEMBL1805309 | 0.86 | OPRL1 (0.48) | OPRL1 | |
| SCHEMBL18579656 | 0.85 | RORC (0.40) | USP2SMN1; SMN2AVPR1AGPR119ESR2 | |
| SCHEMBL21710432 | 0.84 | RORC (0.43) | USP2SMN1; SMN2OPRL1NR1H2 | |
| SCHEMBL31387307 | 0.84 | JAK2 (0.34) | OPRL1 | |
| SCHEMBL26059139 | 0.84 | JAK2 (0.34) | OPRL1 | |
| SCHEMBL18646542 | 0.82 | USP2 (0.35) | USP2SMN1; SMN2AVPR1AGPR119HRH3 | |
| SCHEMBL1807425 | 0.80 | OPRL1 (0.47) | USP2SMN1; SMN2AVPR1AGPR119ESR2 | |
| SCHEMBL26064355 | 0.76 | USP2 (0.36) | USP2SMN1; SMN2AVPR1AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589638-B1 | COMPOUNDS USEFUL FOR INHIBITING ROR-GAMMA-T | LILLY CO ELI (US) | 2021-04-07 | — | — | EP | disclosed |