⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580860 | 0.80 | — | — | |
| SCHEMBL5912837 | 0.67 | LMNA (0.31) | — | |
| SCHEMBL8172004 | 0.67 | — | — | |
| SCHEMBL27939012 | 0.67 | — | — | |
| SCHEMBL1541650 | 0.66 | — | — | |
| SCHEMBL4191544 | 0.65 | — | — | |
| SCHEMBL1481503 | 0.64 | — | — | |
| SCHEMBL28189197 | 0.63 | DNTT (0.31) | — | |
| SCHEMBL10456676 | 0.63 | — | — | |
| SCHEMBL8171997 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658933-A | 1,2, 4-triazolol substituted benzenesulfonamide derivatives | 贵阳学院 | 2024-03-08 | — | — | CN | disclosed |
| EP-2531499-B1 | PROCESS FOR PREPARING VORICONAZOLE BY USING NEW INTERMEDIATES | DONG KOOK PHARM CO LTD (KR) | 2014-07-23 | — | — | EP | disclosed |
| US-8575344-B2 | Process for preparing voriconazole by using new intermediates | DONGKOOK PHARMACEUTICAL CO., LTD. (KR) | 2013-11-05 | — | — | US | disclosed |
| US-20130005973-A1 | PROCESS FOR PREPARING VORICONAZOLE BY USING NEW INTERMEDIATES | DONGKOOK PHARMACEUTICAL CO., LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
| EP-2531499-A2 | PROCESS FOR PREPARING VORICONAZOLE BY USING NEW INTERMEDIATES | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2012-12-12 | — | — | EP | disclosed |
| WO-2011096697-A2 | PROCESS FOR PREPARING VORICONAZOLE BY USING NEW INTERMEDIATES | DONGKOOK PHARMACEUTICAL CO., LTD. (KR) | 2011-08-11 | — | — | WO | disclosed |
| EP-0881220-A1 | DIARYLSULTAM DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-12-02 | — | — | EP | disclosed |
| CN-1067892-A | The preparation method of new pyrrolo-[2,3-b] pyridine derivate | ASTRA AB (SE) | 1993-01-13 | — | — | CN | disclosed |