Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21988107 | 0.86 | AAK1 (0.46) | AAK1CLK1DYRK1AGSK3AGSK3B | |
| SCHEMBL24630092 | 0.85 | AAK1 (0.46) | AAK1CLK1DYRK1ADYRK2DYRK1B | |
| SCHEMBL23166550 | 0.84 | AAK1 (0.45) | AAK1CLK1DYRK1AGSK3AGSK3B | |
| SCHEMBL25024416 | 0.82 | DYRK1A (0.46) | AAK1CLK1DYRK1ADYRK2DYRK1B | |
| SCHEMBL29439040 | 0.81 | AAK1 (0.43) | AAK1GSK3AGSK3BSTK17B | |
| SCHEMBL22049474 | 0.81 | AAK1 (0.43) | AAK1GSK3AGSK3BSTK17B | |
| SCHEMBL22049484 | 0.80 | CLK1 (0.46) | AAK1CLK1DYRK1ADYRK1BGSK3A | |
| SCHEMBL24198035 | 0.79 | GSK3A (0.45) | AAK1TDO2CLK1DYRK1ADYRK2 | |
| SCHEMBL23165619 | 0.79 | MAPT (0.46) | AAK1GSK3AGSK3B | |
| SCHEMBL17324699 | 0.78 | PIK3CA (0.46) | CLK1DYRK1AGSK3AGSK3BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067791-A1 | OXALAMIDE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2021-04-08 | — | — | WO | disclosed |