Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2319488

N.N.O=P(O)(O)CCCCP(=O)(O)O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.79
LPAR3 Q9UBY5 3/20 0.63
LPAR2 Q9HBW0 1/20 0.63
LMNA P02545 1/20 0.61
CYP3A4 P08684 1/20 0.61
NFKB1 P19838 1/20 0.61
BLM P54132 1/20 0.61
PMP22 Q01453 1/20 0.61
BBOX1 O75936 2/20 0.52
ALDH1A1 P00352 3/20 0.50
TDP1 Q9NUW8 1/20 0.48
ENPEP Q07075 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MMP2 P08253 1/20 0.44
THRB P10828 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL5699174 0.96 TYMS (0.73) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL20235 0.96 TYMS (0.85) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL1636300 0.92 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL9701682 0.92 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL7902534 0.92 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL767546 0.92 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
Ammonia Solution, Strong SCHEMBL1643223 0.92 TYMS (0.92) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL3211535 0.92 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
Ammonia Solution, Strong SCHEMBL1777238 0.92 TYMS (0.92) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL630093 0.92 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112705212-B Regeneration method of deactivated residuum hydrotreatment catalyst 中国石油化工股份有限公司 2023-10-10 CN claimed
CN-111647300-A Anti-rust pigment for cathode electrophoretic coating and preparation method of slurry of anti-rust pigment 南昌航空大学 2020-09-11 CN claimed
EP-0015887-B1 IMPROVED LAUNDERING METHOD THE PROCTER & GAMBLE COMPANY (US) 1985-05-08 EP claimed
US-4183915-A Stable solution for dental remineralization COLGATE-PALMOLIVE COMPANY (US) 1980-01-15 US claimed
US-4177258-A Dentifrice for dental remineralization COLGATE PALMOLIVE COMPANY (US) 1979-12-04 US claimed
EP-4400173-A2 ANTI-SIRP ALPHA ANTIBODIES Byondis B.V. (NL) 2024-07-17 EP disclosed
CN-118271443-A Anti-SIRP alpha antibodies 拜奥迪斯私人有限公司 2024-07-02 CN disclosed
WO-2024133374-A1 NOVEL LINKER DRUGS COMPRISING PHOSPHOANTIGENS, NOVEL CONJUGATES AND THEIR USE IN THERAPY BYONDIS B.V. (NL) 2024-06-27 WO disclosed
EP-4362982-A1 CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY Byondis B.V. (NL) 2024-05-08 EP disclosed
CN-110799536-B Anti-SIRP alpha antibodies 拜奥迪斯私人有限公司 2024-04-26 CN disclosed
EP-3625259-B1 ANTI-SIRPALPHA ANTIBODIES BYONDIS BV (NL) 2024-04-17 EP disclosed
CN-117794581-A Conjugates comprising phosphoantigen and their use in therapy 拜奥迪斯私人有限公司 2024-03-29 CN disclosed
WO-1995007685-A1 COMPLEX CALCIUM AND FLUORIDE CONTAINING MOUTH RINSES, DENTIFRICES, AND CHEWABLE TABLETS AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1995-03-23 WO disclosed
CN-1092076-A The target release of growth factors for bone regeneration DOW CHEMICAL CO (US) 1994-09-14 CN disclosed
US-5145668-A Calcium fluoride from calcium chloride and sodium fluorosilicate AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1992-09-08 US disclosed
EP-0165885-B1 LIQUID COMPOSITION FOR THE CLEANING OF HARD SURFACES COTELLE S.A. (FR) 1988-08-31 EP disclosed
EP-0165885-A1 Liquid composition for the cleaning of hard surfaces COTELLE S.A. (FR) 1985-12-27 EP disclosed
US-4265777-A ALSO CONTAINING A SURFACTANT HAVING EFFICIENT SOAP-CURD DISPERSAL PROPERTIES; CLEANING COMPOUNDS; TEXTILES THE PROCTER & GAMBLE COMPANY (US) 1981-05-05 US disclosed
US-4183915-A Stable solution for dental remineralization COLGATE-PALMOLIVE COMPANY (US) 1980-01-15 US disclosed
US-4177258-A Dentifrice for dental remineralization COLGATE PALMOLIVE COMPANY (US) 1979-12-04 US disclosed