Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 0.80 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21450328 | 0.95 | TOP1 (0.79) | TOP1SLC2A1 | |
| SCHEMBL21450505 | 0.94 | TOP1 (0.78) | TOP1SLC2A1 | |
| SCHEMBL26293227 | 0.93 | TOP1 (0.81) | TOP1SLC2A1 | |
| SCHEMBL21450507 | 0.93 | TOP1 (0.75) | TOP1SLC2A1 | |
| SCHEMBL21450354 | 0.91 | TOP1 (0.73) | TOP1SLC2A1 | |
| SCHEMBL21450516 | 0.91 | TOP1 (0.85) | TOP1SLC2A1 | |
| SCHEMBL9563389 | 0.90 | TOP1 (0.76) | TOP1SLC2A1 | |
| SCHEMBL31692117 | 0.90 | TOP1 (0.76) | TOP1SLC2A1 | |
| SCHEMBL25082767 | 0.90 | TOP1 (0.76) | TOP1SLC2A1 | |
| SCHEMBL21450330 | 0.90 | TOP1 (0.83) | TOP1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067861-A1 | CAMPTOTHECIN PEPTIDE CONJUGATES | SEAGEN INC. (US) | 2021-04-08 | — | — | WO | disclosed |