Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 0.76 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26293227 | 0.91 | TOP1 (0.81) | TOP1SLC2A1 | |
| SCHEMBL23196106 | 0.90 | TOP1 (0.80) | TOP1SLC2A1 | |
| SCHEMBL21450328 | 0.90 | TOP1 (0.79) | TOP1SLC2A1 | |
| SCHEMBL9563443 | 0.89 | TOP1 (0.75) | TOP1SLC2A1 | |
| SCHEMBL21450505 | 0.89 | TOP1 (0.78) | TOP1SLC2A1 | |
| SCHEMBL21450516 | 0.89 | TOP1 (0.85) | TOP1SLC2A1 | |
| SCHEMBL21450330 | 0.88 | TOP1 (0.83) | TOP1SLC2A1 | |
| SCHEMBL23196407 | 0.88 | TOP1 (0.75) | TOP1SLC2A1 | |
| SCHEMBL21450507 | 0.88 | TOP1 (0.75) | TOP1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL9563400 | 0.88 | TOP1 (0.81) | TOP1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556585-A2 | Condensed camptothecin derivatives their production and use as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |