Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19132000 | 0.94 | ESR1 (0.87) | ESR1 | |
| SCHEMBL21253418 | 0.94 | ESR1 (0.87) | ESR1 | |
| SCHEMBL31739221 | 0.94 | ESR1 (0.87) | ESR1 | |
| SCHEMBL19154748 | 0.94 | ESR1 (0.89) | ESR1 | |
| SCHEMBL29500085 | 0.94 | ESR1 (0.89) | ESR1 | |
| SCHEMBL31114327 | 0.94 | ESR1 (0.89) | ESR1 | |
| SCHEMBL19131521 | 0.94 | ESR1 (0.89) | ESR1 | |
| SCHEMBL29836645 | 0.94 | ESR1 (0.80) | ESR1ESR2 | |
| SCHEMBL26539693 | 0.94 | ESR1 (0.80) | ESR1ESR2 | |
| SCHEMBL23196305 | 0.93 | ESR1 (0.77) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3847157-B1 | PROCESS FOR THE PREPARATION OF METHYL 6-(2,4-DICHLOROPHENYL)-5-[4-[(3S)-1-(3-FLUOROPROPYL)PYRROLIDIN-3-YL]OXYPHENYL]-8,9-DIHYDRO-7H-BENZO[7]ANNULENE-2-CARBOXYLATE AND A SALT THEREOF | SANOFI SA (FR) | 2022-05-18 | — | — | EP | disclosed |
| WO-2021063967-A1 | NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2021-04-08 | — | — | WO | disclosed |