Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196336 | 0.75 | ACACB (0.35) | GAAPTGS1 | |
| SCHEMBL896479 | 0.74 | GAA (1.00) | GAANPSR1ATMMEN1KMT2A | |
| SCHEMBL23196005 | 0.71 | GLP1R (0.40) | SMN1; SMN2 | |
| SCHEMBL23196350 | 0.70 | GAA (0.62) | GAANPSR1ATMMEN1KMT2A | |
| SCHEMBL18444813 | 0.67 | GAA (0.57) | GAANPSR1ATMMEN1KMT2A | |
| SCHEMBL27457102 | 0.64 | ABL1 (0.32) | — | |
| SCHEMBL20525144 | 0.62 | — | — | |
| SCHEMBL3820019 | 0.62 | GAA (0.48) | GAAPTGS1PTGS2NPSR1ATM | |
| SCHEMBL14618075 | 0.61 | GAA (0.59) | GAANPSR1ATMMEN1KMT2A | |
| SCHEMBL3817278 | 0.61 | GAA (0.65) | GAANPSR1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4023642-A1 | JNK INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021063207-A1 | JNK INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 武汉朗来科技发展有限公司 | 2021-04-08 | — | — | WO | disclosed |