SCHEMBL896479

SCHEMBL896479

CC(C)(C)Oc1ncc(Br)c(OC(C)(C)C)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 1.00
NPSR1 Q6W5P4 2/20 0.47
ATM Q13315 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8387199 0.79 GAA (0.65) GAANPSR1ATMMEN1KMT2A
SCHEMBL3817278 0.78 GAA (0.65) GAANPSR1ATMMEN1KMT2A
SCHEMBL13049649 0.78 GAA (0.65) GAANPSR1ATMMEN1KMT2A
SCHEMBL14586465 0.78 GAA (0.65) GAANPSR1ATMMEN1KMT2A
SCHEMBL29271046 0.77 GAA (0.62) GAANPSR1ATMMEN1KMT2A
SCHEMBL18380993 0.77 GAA (0.62) GAANPSR1ATMMEN1KMT2A
SCHEMBL23196350 0.77 GAA (0.62) GAANPSR1ATMMEN1KMT2A
SCHEMBL561353 0.74 GAA (0.59) GAANPSR1ATMMEN1KMT2A
SCHEMBL14618075 0.74 GAA (0.59) GAANPSR1ATMMEN1KMT2A
SCHEMBL23196348 0.74 GAA (0.58) GAANPSR1ATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271296-A Pseudo-uridine, preparation method and application thereof 北京安必奇生物科技有限公司 2024-07-02 CN disclosed
CN-114940676-B Synthesis method of pseudouridine 天津全和诚科技有限责任公司 2024-01-26 CN disclosed
CN-115894458-A Novel modified nucleoside and application thereof in nucleic acid medicine 合肥华纳生物医药科技有限公司 2023-04-04 CN disclosed
CN-114940676-A Synthesis method of pseudouridine 天津全和诚科技有限责任公司 2022-08-26 CN disclosed
EP-3251674-A2 ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES BioCryst Pharmaceuticals, Inc. (US) 2017-12-06 EP disclosed
US-20170267681-A1 ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES MIDCAP FINANCIAL TRUST, AS AGENT 2017-09-21 US disclosed
US-20170267681-A1 ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES MIDCAP FINANCIAL TRUST, AS AGENT 2017-09-21 US disclosed
US-9637478-B2 Antiviral compounds and uses thereof ABBVIE INC. (US) 2017-05-02 US disclosed
EP-2411352-B1 ANTIVIRAL COMPOUNDS AND USES THEREOF ABBVIE INC (US) 2017-01-18 EP disclosed
US-20160368905-A1 ANTIVIRAL COMPOUNDS AND USES THEREOF ABBOTT LABORATORIES 2016-12-22 US disclosed
WO-1999026944-A1 NEW COMPOUNDS WHICH ARE P2-PURINOCEPTOR 7-TRANSMEMBRANE (TM) G-PROTEIN COUPLED RECEPTOR ANTAGONISTS ASTRAZENEKA UK LIMITED (GB) 1999-06-03 WO disclosed
WO-1999005123-A1 NOVEL PYRIMIDIN DERIVATIVES ASTRAZENECA UK LIMITED (GB) 1999-02-04 WO disclosed
WO-1999002501-A1 NOVEL COMPOUNDS ASTRA PHARMACEUTICALS LTD. (GB) 1999-01-21 WO disclosed
WO-1998054180-A1 NOVEL COMPOUNDS ASTRA PHARMACEUTICALS LTD. (GB) 1998-12-03 WO disclosed
US-5576429-A HUMAN T-CELL LEUKEMIA/LYMPHOMA VIRICIDE; ANTITUMOR AGENT MEDIVIR AB (SE) 1996-11-19 US disclosed
EP-0357571-B1 Pyrimidine nucleosides MEDIVIR AB (SE) 1996-04-03 EP disclosed
EP-0691333-A2 Pyrimidine derivatives, process for their preparation and their use as precursors Medivir Aktiebolag (SE) 1996-01-10 EP disclosed
US-5440040-A Drug for Aids therapy; viricides MEDIVIR AB (SE) 1995-08-08 US disclosed
EP-0357571-A2 Pyrimidine nucleosides Medivir Aktiebolag (SE) 1990-03-07 EP disclosed
WO-1989012061-A1 PYRIMIDINE NUCLEOSIDES AND INTERMEDIATES MEDIVIR AB (SE) 1989-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368905-A1 ANTIVIRAL COMPOUNDS AND USES THEREOF MAVS, ZC3HAV1, EIF2AK2 GAA 246/4885NPSR1 4135/4885ATM 4521/4885
US-20170267681-A1 ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES RNGTT, DUT, RNMT GAA 60/4885NPSR1 3263/4885ATM 4690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.