SCHEMBL23196828

SCHEMBL23196828

c1ccc(-c2nc3c(-c4ccc5c(c4)sc4ccccc45)cccc3c3c2ccc2sc4ccccc4c23)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C8 P10632 1/20 0.36
CYP2C9 P11712 1/20 0.36
DHODH Q02127 1/20 0.36
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LIMK1 P53667 6/20 0.34
ENPP1 P22413 3/20 0.34
F9 P00740 1/20 0.34
PRKDC P78527 1/20 0.33
GPR3 P46089 1/20 0.33
PIM3 Q86V86 1/20 0.32
CRHR1 P34998 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23196839 0.94 MEN1 (0.34) ALOX5CYP3A4CYP2C8CYP2C9DHODH
SCHEMBL23197431 0.93 CYP3A4 (0.36) ALOX5CYP3A4CYP2C8CYP2C9DHODH
SCHEMBL23197547 0.92 CYP3A4 (0.35) ALOX5CYP3A4CYP2C8CYP2C9DHODH
SCHEMBL23197446 0.91 DHODH (0.38) ALOX5CYP3A4CYP2C8CYP2C9DHODH
SCHEMBL23197228 0.90 F9 (0.34) ALOX5CYP3A4CYP2C8CYP2C9DHODH
SCHEMBL23197774 0.90 ALOX5 (0.44) ALOX5CYP3A4CYP2C8CYP2C9DHODH
SCHEMBL23197436 0.89 ENPP1 (0.34) CYP3A4CYP2C8CYP2C9DHODHALDH1A1
SCHEMBL23196838 0.89 MEN1 (0.34) ALOX5CYP3A4CYP2C8CYP2C9DHODH
SCHEMBL23197029 0.88 ATM (0.39) CYP3A4CYP2C8CYP2C9DHODHALDH1A1
SCHEMBL23197776 0.88 LIMK1 (0.33) ALOX5CYP3A4CYP2C8CYP2C9DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021066397-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-04-08 WO disclosed