SCHEMBL23197876

SCHEMBL23197876

CCC1CCC(C2CCC(CCc3cc(F)c(F)c(F)c3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.31
NOS3 P29474 3/20 0.31
NOS1 P29475 3/20 0.31
NOS2 P35228 3/20 0.31
MAOB P27338 3/20 0.30
MAOA P21397 2/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9764466 0.95 RIPK1 (0.33) RIPK1NOS3NOS1NOS2MAOB
SCHEMBL9764462 0.95 RIPK1 (0.33) RIPK1NOS3NOS1NOS2MAOB
SCHEMBL9763919 0.93 RIPK1 (0.33) RIPK1NOS3NOS1NOS2MAOB
SCHEMBL9763913 0.93 RIPK1 (0.33) RIPK1NOS3NOS1NOS2MAOB
SCHEMBL9763924 0.93 RIPK1 (0.33) RIPK1NOS3NOS1NOS2MAOB
SCHEMBL21581487 0.92 MAOB (0.33) NOS3NOS1NOS2MAOBMAOA
SCHEMBL7525081 0.90 TLR4 (0.35) RIPK1NOS3NOS1NOS2MAOB
SCHEMBL7525064 0.90 TLR4 (0.35) RIPK1NOS3NOS1NOS2MAOB
SCHEMBL7507334 0.90 TLR4 (0.35) RIPK1NOS3NOS1NOS2MAOB
SCHEMBL21581491 0.90 MAOB (0.33) NOS3NOS1NOS2MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210102122-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2021-04-08 US disclosed