Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 13/20 | 0.40 |
| ▸ | CA2 | P00918 | 13/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24297332 | 1.00 | BLM (0.57) | BLMPMP22HSD17B10MEN1GAA | |
| SCHEMBL15508687 | 0.96 | BLM (0.50) | BLMPMP22HSD17B10MEN1GAA | |
| SCHEMBL15508735 | 0.91 | BLM (0.45) | BLMPMP22HSD17B10MEN1GAA | |
| SCHEMBL16995569 | 0.91 | BLM (0.45) | BLMPMP22HSD17B10MEN1GAA | |
| SCHEMBL15508694 | 0.91 | TDP1 (0.46) | BLMPMP22HSD17B10MEN1GAA | |
| SCHEMBL31041197 | 0.90 | BLM (0.47) | BLMPMP22HSD17B10MEN1GAA | |
| SCHEMBL24922458 | 0.87 | MEN1 (0.42) | BLMPMP22HSD17B10MEN1GAA | |
| SCHEMBL24668075 | 0.87 | MEN1 (0.42) | BLMPMP22HSD17B10MEN1GAA | |
| SCHEMBL15508697 | 0.86 | TDP1 (0.42) | BLMPMP22HSD17B10MEN1GAA | |
| SCHEMBL25529335 | 0.85 | TDP1 (0.44) | BLMPMP22HSD17B10MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214376-A1 | HALOGENATED BIOTIN-MODIFIED DIMER AND USE THEREOF | THE UNIVERSITY OF TOKYO (JP) | 2021-07-15 | — | — | US | disclosed |
| US-20210214376-A1 | HALOGENATED BIOTIN-MODIFIED DIMER AND USE THEREOF | THE UNIVERSITY OF TOKYO (JP) | 2021-07-15 | — | — | US | disclosed |
| EP-3805235-A1 | HALOGENATED BIOTIN-MODIFIED DIMER AND USE THEREOF | The University of Tokyo (JP) | 2021-04-14 | — | — | EP | disclosed |
| EP-3805235-A1 | HALOGENATED BIOTIN-MODIFIED DIMER AND USE THEREOF | The University of Tokyo (JP) | 2021-04-14 | — | — | EP | disclosed |
| CN-112243441-A | Halogenated biotin-modified dimers and uses thereof | 国立大学法人东京大学 | 2021-01-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214376-A1 | HALOGENATED BIOTIN-MODIFIED DIMER AND USE THEREOF | BTD, BRI3BP, HLCS | BLM 3826/4885PMP22 3752/4885HSD17B10 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.