Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 10/20 | 0.80 |
| ▸ | MAPK10 | P53779 | 10/20 | 0.80 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.80 |
| ▸ | EGFR | P00533 | 2/20 | 0.66 |
| ▸ | INSR | P06213 | 1/20 | 0.64 |
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.64 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.64 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.64 |
| ▸ | CDC7 | O00311 | 1/20 | 0.64 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.64 |
| ▸ | PAK4 | O96013 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | PRKACA | P17612 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 1/20 | 0.64 |
| ▸ | SYK | P43405 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25668162 | 0.90 | EGFR (0.81) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL25668074 | 0.90 | MAPK9 (0.84) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL23200446 | 0.88 | MAPK9 (0.81) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL24044993 | 0.87 | MAPK9 (0.77) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL23200452 | 0.87 | CDK2 (0.80) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL25783801 | 0.85 | MAPK9 (0.68) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL25782340 | 0.85 | PTK2 (0.79) | MAPK9MAPK10MAPK8EGFRINSR | |
| Trifluoroacetic Acid SCHEMBL23200449 | 0.84 | MAPK9 (0.73) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL29915284 | 0.84 | MAPK9 (0.66) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL25668116 | 0.84 | MAPK9 (0.66) | MAPK9MAPK10MAPK8EGFRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3803401-A1 | BROAD-SPECTRUM KINASE BINDING AGENTS | Promega Corporation (US) | 2021-04-14 | — | — | EP | disclosed |