Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 11/20 | 0.77 |
| ▸ | MAPK10 | P53779 | 11/20 | 0.77 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.77 |
| ▸ | EGFR | P00533 | 2/20 | 0.67 |
| ▸ | INSR | P06213 | 1/20 | 0.64 |
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.64 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.64 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.64 |
| ▸ | CDC7 | O00311 | 1/20 | 0.64 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.64 |
| ▸ | PAK4 | O96013 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | PRKACA | P17612 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 1/20 | 0.64 |
| ▸ | SYK | P43405 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24044992 | 0.91 | MAPK9 (0.65) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL24044994 | 0.90 | PTK2 (0.79) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL25668162 | 0.90 | EGFR (0.81) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL25483897 | 0.90 | MAP3K7 (0.66) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL25668074 | 0.88 | MAPK9 (0.84) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL23200445 | 0.87 | MAPK9 (0.80) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL23200446 | 0.86 | MAPK9 (0.81) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL23200452 | 0.84 | CDK2 (0.80) | MAPK9MAPK10MAPK8EGFRINSR | |
| SCHEMBL26508596 | 0.82 | PTK2 (0.75) | INSRPTK2 | |
| SCHEMBL25668157 | 0.81 | EGFR (0.68) | MAPK9MAPK10MAPK8EGFRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230194515-A1 | BROAD SPECTRUM KINASE BINDING AGENTS | PROMEGA CORPORATION | 2023-06-22 | — | — | US | disclosed |
| US-20230194515-A1 | BROAD SPECTRUM KINASE BINDING AGENTS | PROMEGA CORPORATION | 2023-06-22 | — | — | US | disclosed |
| US-20210363565-A1 | ENHANCEMENT OF KINASE TARGET ENGAGEMENT | PROMEGA CORPORATION | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230194515-A1 | BROAD SPECTRUM KINASE BINDING AGENTS | MAP4K2, MAP3K20, MAP4K1 | MAPK9 255/4885MAPK10 241/4885MAPK8 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.