Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | JAK3 | P52333 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | BACE1 | P56817 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17718758 | 0.91 | ACHE (0.57) | ACHEJAK2JAK1TYK2JAK3 | |
| SCHEMBL20624405 | 0.90 | ACHE (0.55) | ACHEJAK2JAK1TYK2JAK3 | |
| SCHEMBL20597477 | 0.85 | BCHE (0.51) | ACHEJAK2JAK1TYK2JAK3 | |
| SCHEMBL2033625 | 0.85 | BCHE (0.51) | ACHEJAK2JAK1TYK2JAK3 | |
| SCHEMBL27035510 | 0.85 | BCHE (0.51) | ACHEJAK2JAK1TYK2JAK3 | |
| SCHEMBL20624030 | 0.82 | ACHE (0.66) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL13636703 | 0.82 | ACHE (0.66) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL9918617 | 0.82 | ACHE (0.66) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL21917967 | 0.80 | ACHE (0.62) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL20624040 | 0.78 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1609781-B1 | Optical resolution of (1-benzyl-4-methylpiperidin-3-yl)-methylamine | PFIZER PROD INC (US) | 2011-08-10 | — | — | EP | claimed |