Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 13/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2056409 | 0.83 | RAB9A (0.70) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL1126145 | 0.77 | RAB9A (0.62) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL21241297 | 0.77 | RAB9A (0.62) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL2636192 | 0.77 | RAB9A (0.78) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL81867 | 0.76 | RAB9A (0.55) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL423961 | 0.75 | RAB9A (0.75) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL5788823 | 0.75 | RAB9A (0.58) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL21678139 | 0.74 | RAB9A (0.72) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL5034164 | 0.74 | RAB9A (0.72) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL30721815 | 0.74 | TDP1 (0.53) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | disclosed |