Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 12/20 | 0.58 |
| ▸ | F2 | P00734 | 11/20 | 0.58 |
| ▸ | F7 | P08709 | 6/20 | 0.54 |
| ▸ | F10 | P00742 | 5/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.54 |
| ▸ | F12 | P00748 | 3/20 | 0.54 |
| ▸ | F9 | P00740 | 1/20 | 0.54 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.46 |
| ▸ | KLK1 | P06870 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23201268 | 1.00 | F11 (0.58) | F11F2F7F10PRSS1 | |
| SCHEMBL23201258 | 1.00 | F11 (0.58) | F11F2F7F10PRSS1 | |
| SCHEMBL6436645 | 0.91 | F11 (0.56) | F11F2F7F10PRSS1 | |
| SCHEMBL6436637 | 0.91 | F11 (0.56) | F11F2F7F10PRSS1 | |
| SCHEMBL23793701 | 0.89 | F11 (0.60) | F11F2F7F10PRSS1 | |
| SCHEMBL7711124 | 0.89 | F11 (0.65) | F11F2F7F10PRSS1 | |
| SCHEMBL6438863 | 0.89 | F11 (0.65) | F11F2F7F10PRSS1 | |
| SCHEMBL29202591 | 0.88 | F11 (0.55) | F11F2F7F10PRSS1 | |
| SCHEMBL25054132 | 0.88 | F11 (0.55) | F11F2F7F10PRSS1 | |
| SCHEMBL29202590 | 0.88 | F11 (0.55) | F11F2F7F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | disclosed |