Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 17/20 | 0.63 |
| ▸ | CCND1 | P24385 | 12/20 | 0.63 |
| ▸ | CCND3 | P30281 | 7/20 | 0.63 |
| ▸ | CCND2 | P30279 | 6/20 | 0.63 |
| ▸ | CDK2 | P24941 | 5/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.57 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.56 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.56 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.55 |
| ▸ | CCNK | O75909 | 2/20 | 0.55 |
| ▸ | CDK9 | P50750 | 2/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194193 | 0.82 | CDK4 (0.58) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL4722863 | 0.82 | CDK4 (0.62) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL18101478 | 0.80 | CDK4 (0.66) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL29507502 | 0.78 | CDK4 (1.00) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL4835935 | 0.78 | CDK4 (1.00) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL13812807 | 0.77 | CDK4 (0.64) | CDK4CCND1CCND3CCND2CDK2 | |
| Hydrochloric Acid SCHEMBL4830677 | 0.77 | CDK4 (0.98) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL20673673 | 0.76 | CCND3 (0.56) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL22113110 | 0.75 | CDK4 (0.59) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL7712824 | 0.75 | CDK4 (0.67) | CDK4CCND1CCND3CCND2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242770-A1 | DRUG-LIKE MOLECULES AND METHODS FOR THE THERAPEUTIC TARGETING OF VIRAL RNA STRUCTURES | UNIVERSITY OF WASHINGTON (US) | 2021-12-02 | — | — | WO | disclosed |
| EP-3802825-A1 | COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY | Intellia Therapeutics, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |