Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 17/20 | 1.00 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31188896 | 1.00 | MC2R (1.00) | MC2RCCR1LMNATSHRRAB9A | |
| SCHEMBL21700871 | 1.00 | MC2R (1.00) | MC2RCCR1LMNATSHRRAB9A | |
| SCHEMBL21700876 | 1.00 | MC2R (1.00) | MC2RCCR1LMNATSHRRAB9A | |
| SCHEMBL21700831 | 0.91 | MC2R (1.00) | MC2RLMNASMN1; SMN2 | |
| SCHEMBL31188485 | 0.91 | MC2R (1.00) | MC2RLMNASMN1; SMN2 | |
| SCHEMBL21700771 | 0.91 | MC2R (1.00) | MC2RCCR1LMNATSHRRAB9A | |
| SCHEMBL21701035 | 0.90 | MC2R (0.84) | MC2R | |
| SCHEMBL21700856 | 0.87 | MC2R (0.92) | MC2RLMNASMN1; SMN2 | |
| SCHEMBL21700664 | 0.86 | MC2R (0.76) | MC2RLMNA | |
| SCHEMBL31188558 | 0.86 | MC2R (0.76) | MC2RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | claimed |