Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 16/20 | 0.61 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21700622 | 1.00 | MC2R (0.61) | MC2RHTR1BENPP2PPARG | |
| SCHEMBL30138137 | 0.94 | MC2R (0.61) | MC2RHTR1B | |
| SCHEMBL26641078 | 0.91 | MC2R (0.61) | MC2RHTR1BENPP2PPARG | |
| SCHEMBL26641073 | 0.91 | MC2R (0.61) | MC2RHTR1BENPP2PPARG | |
| SCHEMBL30138124 | 0.90 | MC2R (0.55) | MC2RHTR1BENPP2PPARG | |
| SCHEMBL30138115 | 0.89 | MC2R (0.80) | MC2RHTR1BENPP2PPARG | |
| SCHEMBL31188878 | 0.89 | MC2R (0.80) | MC2RHTR1BENPP2PPARG | |
| SCHEMBL30138119 | 0.88 | MC2R (0.61) | MC2RHTR1B | |
| SCHEMBL21700496 | 0.88 | MC2R (0.77) | MC2RHTR1B | |
| Trifluoroacetic Acid SCHEMBL30138108 | 0.87 | MC2R (0.57) | MC2RHTR1BENPP2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |