Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 16/20 | 0.67 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21700650 | 1.00 | MC2R (0.67) | MC2RHTR1BDGAT2HCRTR1HCRTR2 | |
| SCHEMBL21700703 | 0.91 | MC2R (0.70) | MC2RHTR1BDGAT2ACP1 | |
| SCHEMBL21700486 | 0.91 | MC2R (0.70) | MC2RHTR1BDGAT2ACP1 | |
| SCHEMBL21700578 | 0.91 | MC2R (0.65) | MC2RHTR1BHCRTR1HCRTR2ACP1 | |
| SCHEMBL21700722 | 0.90 | MC2R (0.69) | MC2RHTR1BDGAT2ACP1 | |
| SCHEMBL21700619 | 0.89 | MC2R (0.75) | MC2RHTR1BDGAT2ACP1 | |
| Formic Acid SCHEMBL21700938 | 0.86 | MC2R (0.72) | MC2RHTR1BDGAT2ACP1 | |
| SCHEMBL21700597 | 0.86 | MC2R (0.67) | MC2RHTR1BDGAT2ACP1 | |
| SCHEMBL21700940 | 0.86 | MC2R (0.69) | MC2RHTR1BDGAT2ACP1 | |
| SCHEMBL21700519 | 0.85 | MC2R (0.66) | MC2RHTR1BDGAT2ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |