Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 19/20 | 0.67 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21700575 | 1.00 | MC2R (0.67) | MC2RHCRTR1HCRTR2 | |
| SCHEMBL21700694 | 0.93 | MC2R (0.76) | MC2R | |
| SCHEMBL21700744 | 0.93 | MC2R (0.76) | MC2R | |
| SCHEMBL21700907 | 0.93 | MC2R (0.68) | MC2R | |
| SCHEMBL23201596 | 0.93 | MC2R (0.68) | MC2R | |
| SCHEMBL21700980 | 0.92 | MC2R (0.67) | MC2RHCRTR1HCRTR2 | |
| SCHEMBL28539410 | 0.92 | MC2R (0.56) | MC2RHCRTR1HCRTR2 | |
| SCHEMBL23201638 | 0.92 | MC2R (0.72) | MC2R | |
| SCHEMBL23201609 | 0.92 | MC2R (0.72) | MC2R | |
| SCHEMBL21700947 | 0.92 | MC2R (0.72) | MC2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | claimed |