SCHEMBL23201647

SCHEMBL23201647

CC(=O)N1CC(O)CC1C(N)=O

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.69
MMP2 P08253 2/20 0.47
ANPEP P15144 2/20 0.47
PIK3CD O00329 3/20 0.38
DPP4 P27487 6/20 0.38
DPP8 Q6V1X1 6/20 0.38
DPP9 Q86TI2 6/20 0.38
VHL P40337 4/20 0.36
ALDH1A1 P00352 1/20 0.36
PIK3CA P42336 2/20 0.36
PIK3CG P48736 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
FAP Q12884 1/20 0.36
PIN1 Q13526 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13237028 1.00 ATM (0.69) ATMMMP2ANPEPPIK3CDDPP4
SCHEMBL23897306 0.85 ATM (0.65) ATMMMP2ANPEPPIK3CDDPP4
SCHEMBL8203665 0.84 ATM (0.48) ATMMMP2ANPEPALDH1A1PIN1
SCHEMBL3058678 0.84 ANPEP (0.66) ATMMMP2ANPEPPIN1
SCHEMBL21105707 0.83 ATM (0.47) ATMPIK3CDDPP4DPP8DPP9
SCHEMBL12562519 0.83 ATM (0.74) ATMMMP2ANPEPPIK3CDDPP4
SCHEMBL29489487 0.83 ATM (0.47) ATMPIK3CDDPP4DPP8DPP9
Oxaceprol SCHEMBL25978 0.82 ATM (1.00) ATMMMP2ANPEPPIK3CDDPP4
Oxaceprol SCHEMBL3780150 0.82 ATM (1.00) ATMMMP2ANPEPPIK3CDDPP4
Oxaceprol SCHEMBL25977 0.82 ATM (1.00) ATMMMP2ANPEPPIK3CDDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210101990-A1 COMPOSITIONS AND METHODS FOR THE DEPLETION OF CD134+ CELLS Magenta Therapeutics, Inc. (US) 2021-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210101990-A1 COMPOSITIONS AND METHODS FOR THE DEPLETION OF CD134+ CELLS CD2, CD47, CD22 ATM 4473/4885MMP2 4595/4885ANPEP 658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.