Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13237028 | 0.84 | ATM (0.69) | ATMMMP2ANPEPPIN1ALDH1A1 | |
| SCHEMBL23201647 | 0.84 | ATM (0.69) | ATMMMP2ANPEPPIN1ALDH1A1 | |
| SCHEMBL16349656 | 0.83 | ATM (0.52) | ATMMMP2ANPEPPEPDCHRNB2 | |
| SCHEMBL16300591 | 0.83 | ATM (0.52) | ATMMMP2ANPEPPEPDCHRNB2 | |
| SCHEMBL12161943 | 0.83 | ATM (0.52) | ATMMMP2ANPEPPEPDCHRNB2 | |
| SCHEMBL16300601 | 0.83 | ATM (0.52) | ATMMMP2ANPEPPEPDCHRNB2 | |
| SCHEMBL16300600 | 0.83 | ATM (0.52) | ATMMMP2ANPEPPEPDCHRNB2 | |
| SCHEMBL16748604 | 0.82 | ATM (0.71) | ATMMMP2ANPEPPEPDCHRNB2 | |
| SCHEMBL10283713 | 0.82 | ATM (0.71) | ATMMMP2ANPEPPEPDCHRNB2 | |
| SCHEMBL3058678 | 0.80 | ANPEP (0.66) | ATMMMP2ANPEPPIN1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033389-A2 | MACROCYCLIC HCV INHIBITORS AND THEIR USES | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |