Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 15/20 | 0.72 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | LIPC | P11150 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31188834 | 0.92 | MC2R (0.71) | MC2RP2RX7MRGPRX4 | |
| SCHEMBL21701026 | 0.92 | MC2R (0.71) | MC2RP2RX7MRGPRX4 | |
| SCHEMBL31113398 | 0.89 | MC2R (0.91) | MC2RP2RX7MRGPRX4 | |
| SCHEMBL21700793 | 0.89 | MC2R (0.91) | MC2RP2RX7MRGPRX4 | |
| SCHEMBL21700905 | 0.84 | MC2R (0.61) | MC2RLIPCLIPGLPL | |
| SCHEMBL21700680 | 0.84 | MC2R (1.00) | MC2RMRGPRX4 | |
| SCHEMBL21700838 | 0.83 | MC2R (0.88) | MC2RP2RX7 | |
| SCHEMBL21700840 | 0.83 | MC2R (0.88) | MC2RP2RX7 | |
| SCHEMBL21700797 | 0.83 | MC2R (1.00) | MC2RRORCMRGPRX4 | |
| SCHEMBL21700604 | 0.81 | MC2R (0.60) | MC2RP2RX7MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |