SCHEMBL23201868

SCHEMBL23201868

COC(=O)C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NC(=O)c1cc(Cl)ccc1Cl

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PSMB5 P28074 12/20 0.66
▸ LMNA P02545 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ P2RX1 P51575 2/20 0.47
▸ TMPRSS4 Q9NRS4 2/20 0.47
▸ ITGB1 P05556 1/20 0.46
▸ ITGA4 P13612 1/20 0.46
▸ MCL1 Q07820 1/20 0.45
▸ PYGL P06737 1/20 0.45
▸ PSMB11 A5LHX3 3/20 0.43
▸ PSMA7 O14818 3/20 0.43
▸ PSMB1 P20618 3/20 0.43
▸ PSMA1 P25786 3/20 0.43
▸ PSMA2 P25787 3/20 0.43
▸ PSMA3 P25788 3/20 0.43
▸ PSMA4 P25789 3/20 0.43
▸ PSMB8 P28062 3/20 0.43
▸ PSMB9 P28065 3/20 0.43
▸ PSMA5 P28066 3/20 0.43
▸ PSMB4 P28070 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23201866 1.00 PSMB5 (0.66) PSMB5LMNAHPGDP2RX1TMPRSS4
SCHEMBL21583765 0.91 PSMB5 (0.66) PSMB5LMNAHPGDITGB1ITGA4
SCHEMBL21581969 0.91 PSMB5 (0.66) PSMB5LMNAHPGDITGB1ITGA4
SCHEMBL23201831 0.88 PSMB5 (0.66) PSMB5LMNAHPGDP2RX1TMPRSS4
SCHEMBL23201830 0.88 PSMB5 (0.66) PSMB5LMNAHPGDP2RX1TMPRSS4
SCHEMBL21583785 0.83 PSMB5 (0.50) PSMB5LMNAHPGDTMPRSS4ITGB1
SCHEMBL23221762 0.81 PSMB5 (0.69) PSMB5LMNAHPGDP2RX1TMPRSS4
SCHEMBL23221759 0.80 PSMB5 (1.00) PSMB5PSMB11PSMA7PSMB1PSMA1
SCHEMBL21581967 0.79 ITGB1 (0.67) PSMB5LMNAHPGDITGB1ITGA4
SCHEMBL21581968 0.79 ITGB1 (0.67) PSMB5LMNAHPGDITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805237-B1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND JIANGSU CHUANGTE PHARMACEUTICAL TECH CO LTD (CN) 2026-01-28 — — EP disclosed
US-11542283-B2 Synthesis of peptide borate ester compound and use thereof JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) 2023-01-03 — — US disclosed
US-20210214377-A1 SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) 2021-07-15 — — US disclosed
EP-3805237-A1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) 2021-04-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210214377-A1 SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF SEM1, VIP, PSMB11 PSMB5 38/4885LMNA 2689/4885HPGD 2888/4885
US-11542283-B2 Synthesis of peptide borate ester compound and use thereof SEM1, VIP, PSMB11 PSMB5 38/4885LMNA 2689/4885HPGD 2888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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