Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 8/20 | 0.66 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 4/20 | 0.51 |
| ▸ | NOS3 | P29474 | 2/20 | 0.51 |
| ▸ | NOS1 | P29475 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.45 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.45 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.45 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.45 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.45 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21583765 | 1.00 | PSMB5 (0.66) | PSMB5ITGB1ITGA4NOS2NOS3 | |
| SCHEMBL23201868 | 0.91 | PSMB5 (0.66) | PSMB5ITGB1ITGA4NOS2NOS3 | |
| SCHEMBL23201866 | 0.91 | PSMB5 (0.66) | PSMB5ITGB1ITGA4NOS2NOS3 | |
| SCHEMBL21581968 | 0.88 | ITGB1 (0.67) | PSMB5ITGB1ITGA4MCL1LMNA | |
| SCHEMBL21581967 | 0.88 | ITGB1 (0.67) | PSMB5ITGB1ITGA4MCL1LMNA | |
| SCHEMBL3995599 | 0.87 | PSMB5 (0.51) | PSMB5NOS2NOS3NOS1MCL1 | |
| SCHEMBL21583785 | 0.85 | PSMB5 (0.50) | PSMB5ITGB1ITGA4MCL1LMNA | |
| SCHEMBL4833914 | 0.82 | CDK2 (0.50) | PSMB5NOS2NOS3NOS1CDK2 | |
| SCHEMBL4831953 | 0.82 | CDK2 (0.50) | PSMB5NOS2NOS3NOS1CDK2 | |
| SCHEMBL29359826 | 0.80 | PYGL (0.77) | PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2021-07-15 | — | — | US | disclosed |
| EP-3805237-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| EP-3805237-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| CN-112384519-A | Synthesis and application of peptide borate compound | 江苏正大丰海制药有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-110540547-A | Synthesis and application of peptide borate compound | QIN YANRU | 2019-12-06 | — | — | CN | disclosed |
| WO-2019228299-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | 江苏正大丰海制药有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |
| WO-2019228299-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | 江苏正大丰海制药有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | SEM1, VIP, PSMB11 | PSMB5 38/4885ITGB1 4133/4885ITGA4 4362/4885 |
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | SEM1, VIP, PSMB11 | PSMB5 38/4885ITGB1 4133/4885ITGA4 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.