SCHEMBL23204276

SCHEMBL23204276

CCCN(Cc1ccc(CNC(=O)OC(C)(C)C)cc1)C(=O)C1=Cc2ccc(C(=O)Nc3ccccc3)cc2N=C(N)C1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 20/20 0.70
▸ TLR7 Q9NYK1 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22771316 0.88 TLR8 (0.76) TLR8TLR7
SCHEMBL23166318 0.87 TLR8 (0.72) TLR8TLR7
SCHEMBL23204251 0.86 TLR8 (0.88) TLR8TLR7
SCHEMBL22783809 0.86 TLR8 (0.81) TLR8TLR7
SCHEMBL29778139 0.86 TLR8 (0.81) TLR8TLR7
SCHEMBL22796634 0.84 TLR8 (0.67) TLR8TLR7
SCHEMBL18041279 0.84 TLR8 (1.00) TLR8TLR7
SCHEMBL24698694 0.83 TLR8 (0.65) TLR8TLR7
SCHEMBL20841160 0.82 TLR8 (0.85) TLR8TLR7
SCHEMBL21413437 0.81 TLR8 (0.82) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021067242-A1 AMIDE-LINKED, AMINOBENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2021-04-08 — — WO disclosed
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