SCHEMBL29778139

SCHEMBL29778139

CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CNC(=O)OC(C)(C)C)c3)cc2N=C(N)C1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 20/20 0.81
▸ TLR7 Q9NYK1 4/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22783809 1.00 TLR8 (0.81) TLR8TLR7
SCHEMBL20492761 0.90 TLR8 (0.83) TLR8TLR7
SCHEMBL18041421 0.89 TLR8 (1.00) TLR8TLR7
SCHEMBL20841037 0.89 TLR8 (0.84) TLR8TLR7
SCHEMBL20840991 0.88 TLR8 (0.84) TLR8TLR7
SCHEMBL23652027 0.88 TLR8 (0.86) TLR8TLR7
SCHEMBL23203875 0.88 TLR8 (0.63) TLR8TLR7
SCHEMBL20841075 0.87 TLR8 (0.84) TLR8TLR7
SCHEMBL25688242 0.87 TLR8 (0.64) TLR8TLR7
SCHEMBL18041434 0.87 TLR8 (1.00) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220347310-A1 AMIDE-LINKED, AMINOBENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2022-11-03 — — US disclosed
EP-4038053-A1 AMIDE-LINKED, AMINOBENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF Bolt Biotherapeutics, Inc. (US) 2022-08-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220347310-A1 AMIDE-LINKED, AMINOBENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF AADAC, IGLV6-57, BCR TLR8 535/4885TLR7 608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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